Company:  ISIS PHARMACEUTICALS INC (ISIS)
Form Type:  SC 13G/A
Filing Date:  2/10/2012 
CIK:  0000874015 
Address:  2855 GAZELLE COURT 
City, State, Zip:  CARLSBAD, California 92010 
Telephone:  (760) 931-9200 
Fiscal Year:  12/31 
Last Trade
Last Trade: 
$20.99   		Change: 
0.345 (1.67%)  
Trade Time: 
03:56 PM EST   		Market Cap: 
$2.34B
Description of Business
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  FORM SC 13G/A
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