Company:  ISIS PHARMACEUTICALS INC (ISIS)
Form Type:  SC 13G/A
Filing Date:  2/7/2012 
CIK:  0000874015 
Address:  2855 GAZELLE COURT 
City, State, Zip:  CARLSBAD, California 92010 
Telephone:  (760) 931-9200 
Fiscal Year:  12/31 
Last Trade
Last Trade: 
$22.97   		Change: 
-0.1115 (-0.48%)  
Trade Time: 
09:32 AM EST   		Market Cap: 
$2.57B
Description of Business
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  FORM SC 13G/A
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