Company:  OSIRIS THERAPEUTICS, INC. (OSIR)
Form Type:  10-K
Filing Date:  3/17/2008 
CIK:  0001360886 
Address:  7015 ALBERT EINSTEIN DRIVE 
City, State, Zip:  COLUMBIA, Maryland 21046 
Telephone:  443-545-1819 
Fiscal Year:  12/31 
Last Trade
Last Trade: 
$10.84   		Change: 
-0.43 (-3.82%)  
Trade Time: 
12:39 PM EST   		Market Cap: 
$356.98M
Description of Business
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  FORM 10-K
    PART I
      Item 1. Business.
        NAME AND TITLE
      Item 1A. Risk Factors.
      Item 1B. Unresolved Staff Comments.
      Item 2. Properties.
      Item 3. Legal Proceedings.
      Item 4. Submission of Matters to a Vote of Securities Holders.
    PART II
      Item 5. Market for Registrant's Common Equity, Related ...
      Item 6. Selected Financial Data.
      Item 7. Management's Discussion and Analysis of Financial ...
        Results of Operations
        Liquidity and Capital Resources
      Item 7A. Quantitative and Qualitative Disclosures About ...
      Item 8. Financial Statements and Supplementary Data.
        REPORT OF INDEPENDENT REGISTERED PUBLIC ACCOUNTING FIRM
        REPORT OF INDEPENDENT REGISTERED PUBLIC ACCOUNTING FIRM
        BALANCE SHEET
        INCOME STATEMENT
        STOCKHOLDERS EQUITY
        CASH FLOW
        NOTES TO FINANCIAL STATEMENTS
          BALANCE SHEET
    Part III
      Item 9. Changes in and Disagreements with Accountants on ...
      Item 9A. Controls and Procedures.
      Item 9B. Other Information.
      Item 10. Directors, Executive Officers and Corporate ...
      Item 11. Executive Compensation.
      Item 12. Security Ownership of Certain Beneficial Owners ...
      Item 13. Certain Relationships and Related Transactions, ...
      Item 14. Principal Accounting Fees and Services.
    Part IV
      Item 15. Exhibits, Financial Statement Schedules.
    Report of Independent Registered Public Accounting Firm-Internal
    Report of Independent Registered Public Accounting ...
    Signatures
  EXHIBIT 10.42
  EXHIBIT 10.43
  EXHIBIT 23.1.1
    CONSENT OF INDEPENDENT REGISTERED PUBLIC ACCOUNTING FIRM
  EXHIBIT 31.1.1
    Certification of Principal Executive Officer
  EXHIBIT 31.2.1
    Certification of Principal Financial Officer
  EXHIBIT 32.1.1
    Certification
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