Company:  AEGLEA BIOTHERAPEUTICS, I ... (AGLE)
Form Type:  DEF 14A
Filing Date:  4/21/2017 
CIK:  0001636282 
Address:  901 S. MOPAC EXPRESSWAY, STE. 250
BARTON OAKS PLAZA ONE
 
City, State, Zip:  AUSTIN, Texas 78746 
Telephone:  (512) 942-2935 
Fiscal Year:  12/31 
Last Trade
Last Trade: 
$3.70  
Change: 
0.08 (2.21%)  
Trade Time: 
Jul 21  
Market Cap: 
$60.87M
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© 2017  
Description of Business
We are a biotechnology company committed to developing enzyme-based therapeutics in the field of amino acid metabolism to treat rare genetic diseases and cancer. Our engineered human enzymes are designed to degrade specific amino acids in the blood to target these diseases. In inborn errors of metabolism, or IEM, a subset of rare genetic diseases, we are seeking to reduce the toxic levels of amino acids in patients to the normal range. In oncology, we are seeking to reduce amino acid blood levels below the normal range where we believe we will be able to exploit the dependence of certain cancers on specific amino acids. Our lead product candidate, AEB1102 (pegzilarginase), is engineered to degrade the amino acid arginine and is being developed to treat two extremes of arginine metabolism, including arginine excess in patients with Arginase I deficiency, an IEM, as well as some cancers which have been shown to have a metabolic dependence on arginine.
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  FORM DEF 14A
    NOTICE OF ANNUAL MEETING OF STOCKHOLDERS TO BE HELD ON JUNE ...
    PROXY STATEMENT FOR 2017 ANNUAL MEETING OF STOCKHOLDERS
    Compensation Committee Interlocks and Insider Participation
    PROPOSAL NO. 1
      NAME AND TITLE
      NAME AND TITLE
      COMPENSATION TABLE
    Non-Employee Director Compensation Arrangements
    PROPOSAL NO. 2
    PROPOSAL NO. 3
    SECURITY OWNERSHIP OF CERTAIN BENEFICIAL OWNERS AND MANAGEMENT
      BENEFICIAL OWNERS
      NAME AND TITLE
    EXECUTIVE COMPENSATION
      OPTIONS AGGREGATE
    REPORT OF THE AUDIT COMMITTEE
    Stockholder Proposals to be Presented at Next Annual Meeting
    OTHER MATTERS
    THIS PROXY CARD IS VALID ONLY WHEN SIGNED AND DATED. KEEP ...